ceesdekker Can Be Fun For Anyone

ceesdekker Can Be Fun For Anyone

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Nanotechnology provides A variety of prospects to add to biology. Here I will existing examples the place nanofabrication – the opportunity to make confined buildings with dimensions at will – is employed to look at the biophysics of solitary molecules and cells. I'll current some illustrations from our lab:

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I am able to barely think about how I, like a geneticist, would be capable to find out basic physics, let alone contend at the highest. How did you go about this?

2010, developed a brand new way (‘wedging transfer’) to control nanostructures; 1st report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this assess the elemental job of spatial confinement within the molecular and mobile stage. Our assignments incorporate the next:

Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is demonstrated in gray, the rim of your pore is highlighted in pink, and a 3D rendering with the motion from the DNA rod is exhibited.

Let's say, rather than working with traditional major-down silicon electronics, transistors may be built from The underside up using solitary organic molecules since the switching features? This idea, which turned the basis of nowadays’s field of molecular electronics, 1st emerged in the seventies.

There was one issue even though — we did not observe any measurable ceesdekker electrical conduction from the single polymer molecules. We concluded that at the single-molecule level, conducting polymers had been really not this sort of wonderful conductors, which was relatively disappointing. We Consequently broadened our watch to test to search out extra promising molecules.

An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes

2006, first demonstration of molecular sorting within a lab over a chip using biomotors; discovery of nanobubbles in strong-condition nanopores; and initially estimate of electrokinetic energy conversion within a nanofluidic channel

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes

 Lastly, I will briefly sketch a few of our Tips to check out the making of artificial cells, specially our initially ways to determine artificial mobile division.